PoliPhase Sealant

Not just another hemostat

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That unexpected splenic nick during a routine spay. The enucleation where the optic nerve just won't stop oozing. The tumor removal that encounters a vessel you didn't anticipate. A biliary leak that threatens to extend surgery time and complicate recovery.

These moments don't schedule appointments - but you can be ready for them.

PoliPhase is the surgical confidence every procedure deserves - whether you're reinforcing a planned anastomosis or managing an unexpected bleed. Because when you need absolute certainty that your repair will hold, PoliPhase delivers.

Beyond Hemostasis: A True Physical Seal

Creates an Actual Structural Seal

Not just a hemostat. PoliPhase combines bovine serum albumin (BSA) and a crosslinker to bind directly with tissue proteins, creating a flexible physical seal that stops fluid leakage at the source—regardless of clotting ability.

Fast, Reliable Performance

Regain control in approximately 20 seconds. While we've always said "under a minute," the real truth is that most surgeons regain control of bleeding sites in about 20 seconds. Every batch is quality tested for seal time before release.

Minimal Inflammatory Response

Designed for patient safety. PoliPhase is fully resorbable (typically 25-30 days) with minimal to no inflammatory response—a significant advantage over products whose hemostatic components can trigger inflammation in sensitive patients.

No Heat Generation

Endothermic formulation. Unlike cyanoacrylate glues that generate heat, PoliPhase is endothermic—it actually feels slightly cool to the touch after curing. No thermal damage to delicate tissues.

Our Confidence Guarantee

We believe so strongly that every hospital should have PoliPhase ready for emergencies that if you don't use yours before expiration, we'll replace it once—free.

Because having it when you need it? Priceless.

Proven in Research

Backed by published studies. Research published in the American Journal of Veterinary Research demonstrates significantly higher leakage pressures at anastomotic sites with PoliPhase application, with no tissue deformation or stricture formation.

PoliPhase is packaged as a sterile, 2.5ml double-chambered syringe, supplied with two standard surgical mixing tips.

Want to take the science deep dive? Check out our Resources page.

Applications For Use

  • Anastomotic suture lines – Reinforce intestinal, gastric, or urinary repairs

  • Enucleations – Seal the optic nerve stump to prevent post-operative oozing

  • Tumor removals – Control bleeding from resection sites

  • Biliary leaks – Seal liver repairs and bile duct procedures

  • Internal lacerations – Address unexpected tissue trauma during surgery

  • Splenic repairs – Manage tears and nicks that continue seeping despite suturing

  • Any surgical "oops" moment – Your safety net when the unexpected happens

Additional Resources

PoliPhase Surgical Sealant →
Cadaver Study →
PoliPhase MSDS →
PoliPhase Impant Study →
  • "Your products are just awesome. Thank you for all you do and for your personal interest!"

    Sarita S., Albuquerque, NM

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